Cubs vs. White Sox: Wrigley Field Pitcher Set for 8:05 PM ET, White Sox at +154 in MLB Odd
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First pitch from Wrigley Field is set for 8:05 p.m. ET. The Cubs are -172 on the money line (risk $172 to win $100) in the latest White Sox vs. Cubs odds, with the White Sox at +154. The over/under for total runs is 9. Before making any White Sox vs. Cubs picks, be sure to see the White Sox vs. Cubs predictions and betting advice from SportsLine's proven computer model.
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SB NationTensions were high in the first game of the series, and not just on the field. The Cubs beat the White Sox, 7-5, thanks to a dramatic 10th inning walkoff homer from possible MVP Pete Crow-Armstrong. The two teams traded the lead back and forth all night, with the Sox striking first on a three-run blast by Randal Grichuk, the Cubs forging ahead on a throwing error by Miguel Vargas, and then the Sox coming back on an eighth inning pinch hit home run from Andrew Benintendi.
ESPNPCA 1st since 2010 with leadoff, walk-off homers Centerfielder and MVP candidate Pete Crow-Armstrong launched two home runs -- to lead off the game and to walk it off hours later -- as the Chicago Cubs authored a 7-5, 10-inning victory over the rival Chicago White Sox at Wrigley Field on Monday night.
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The latest DraftKings promo code gives new users $150 in bonus bets after making a first wager of $5 or more, and on Tuesday, fans of MLB rivalries can use this sportsbook promo on the Crosstown Classic of Cubs vs. White Sox. After a 7-5 Cubs win in 10 innings on Monday, the SportsLine Projection Model expects another close contest, backing the White Sox to cover as 1.5-run underdogs on the run line as part of Tuesday's MLB best bets at DraftKings Sportsbook.
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Tuesday best bets at BetMGM Sportsbook White Sox (+1.5) vs. Cubs (-155) Marlins (+1.5) vs. Phillies (-105) Pete Alonso, Orioles, Over 1.5 total bases (+125)
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Combining the three picks into Tuesday at DraftKings would result in a payout of +597 (risk $100 to profit $597, odds subject to change). Claim $150 in bonus bets after your first $5 wager at DraftKings here:
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The SportsLine Projection Model simulates every MLB game 10,000 times and entered Week 22 of the MLB season on a sizzling 49-31 run on all top-rated MLB picks. It also excelled at making home run prop picks in 2025, returning nearly 30 units of profit if you had entered its picks at the . Anyone following its MLB betting picks with sportsbook promos on betting apps could have seen strong returns.
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Pete Alonso, Orioles, Over 1.5 total bases (+125) "Pete Alonso is on a ridiculous tear, and let's take advantage on Tuesday against the Yankees and Carlos Rodon," SportsLine expert Eric Cohen said. "Alonso is riding a nine-game hitting streak and is 18-for-34 (.529) during that time. The Orioles first baseman has gone Over this prop in eight of those nine games, including five home runs and seven total extra-base hits. Against Carlos Rodon, who returns off the injured list, Alonso is 2-for-10 with a home run in his career. I'll ride the hot streak until it ends, especially at plus money." Back Alonso by claiming the latest BetMGM bonus code CBSSPORTS here:
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SportsLine picks -- Model: Twins +1.5 (-155) | Expert: Braves ML (-125, Eric Cohen)
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Braves (-131) to defeat Twins I'm backing Atlanta's new acquisition, pitcher Tyler Mahle, who has given up only one run in 12 innings since being acquired in early August," SportsLine expert Eric Cohen said. "Meanwhile, Minnesota's Zebby Matthews posted a 7.66 ERA in July and a 6.30 ERA thus far in August. With the wind blowing out to right field, look for the Braves' left-handed power hitters (Matt Olson, Drake Baldwin, Michael Harris, Ozzie Albies) to crush the homer-prone Matthews (18 home runs allowed in 91 innings). I think Atlanta bounces back Tuesday night on the road." Bet on the Braves at DraftKings here and claim $150 in bonus bets after your first $5 wager as a new user:
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01 CBS Sports The model is also backing the Marlins to cover as 1.5-run underdogs on the run line. SportsLine expert Eric Cohen has locked in an MLB player prop pick on Yankees vs. Orioles for Tuesday MLB best bets at BetMGM. The over/under for total runs scored in Yankees vs. Orioles is 8.5. Claim the latest BetMGM bonus code CBSSPORTS and bet on Tuesday's top games:
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02 SB Nation The Chicago Cubs and Chicago White Sox are playing a rare crosstown series that actually matters this week at Wrigley Field. The White Sox are MLB’s biggest surprise this season, entering the week in first place in the AL Central with a 5.5 game lead over three other teams. The Cubs are the NL’s top wildcard team at the moment, and are hoping to chase down the Milwaukee Brewers for the division title by the end of the regular season.
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